This is a very cool prompt and allows for a lot of creative freedom and options, so I think some ISFL/DSFL matchups would be fun. The first one I can think of is Tijuana and Arizona as they work well together for numerous reasons. Geographically they are two of the closest teams possible as they're really right across the border from each other. They also both have a lot of history as they both went on dominant runs earlier this decade. I mean even current Arizona QB Puddles O'Duck was a luchador, the fit is just spectacular. The other ISFL/DSFL matchup I have is based more on personal experience then anything, but Portland and Berlin would be fun. I'm one of many Portland alumnus currently on Berlin with many other important players also being former Pythons. I also think a Fire Python logo would look absolutely beautiful, I need to see one of those made soon.
SAVE THE WIKI!